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According to the CDC, pipe and cigar smoke contain many of the same toxic and cancer-causing chemicals as cigarette smoke

First cultivated by people in Central America an estimated 7,000 years ago, the plant spread to Europe when colonial trade was established across the Atlantic, making it an economic fixture of the American colonies and, eventually, the United States

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[43] Further studies have concluded that the olfactory loss may be associated with intellectual disability, rather than any Alzheimer's disease-like pathology